[3] “Other estimates include […] a range of $20,000-$100,000 per quality-adjusted life-years reported in Canada. Some argue that these cost-effectiveness threshold estimates may be too high, and are contributing to escalating healthcare costs; others argue that they are too low.” Cameron, C.G. & Bennett, H.A. (2009). Appendix 2 of Cost-effectiveness of insulin analogues for diabetes mellitus. CMAJ, 180(4), 400-407. Retrieved from http://www.cmaj.ca/content/180/4/400